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Formaldehyde, like methanol, is a versatile chemical that enables manufacture of an even larger variety of successful commercial chemicals. It was discovered in 1859, and has been manufactured since the beginning of the twentieth century. Formaldehyde derivatives serve a wide variety of end uses such as wood products, plastics, and coatings.

Acetic acid is a well-developed intermediate used in several successful commercial chemical processes. Eventual applications for acetic acid derivatives include latex emulsion resins for paints, adhesives, paper coatings, textile finishing agents, cellulose acetate fibers, cigarette filter tow, and cellulosic plastics.